| Boston BOS | | | | Nick Pivetta vs Jorge Lopez | |
| Chicago CHC | | | | Trevor Williams vs JT Brubaker | |
| Los Angeles LAA | | | | Alex Cobb vs Sin decisión | |
| Detroit DET | | | | Jose Urena vs Logan Allen | |
| Miami MIA | | | | Sin decisión vs Marcus Stroman | |
| New York NYY | | | | Jordan Montgomery vs Brent Honeywell Jr. | |
| Kansas City KC | | | | Mike Minor vs Dylan Cease | |
| Seattle SEA | | | | Chris Flexen vs Matt Shoemaker | |
| Milwaukee MIL | | | | Brett Anderson vs Daniel Ponce de Leon | |
| San Diego SD | | | | Adrian Morejon vs Mike Foltynewicz | |
| Colorado COL | | | | German Marquez vs Anthony DeSclafani | |
| Cincinnati CIN | | | | Jose De Leon vs Luke Weaver | |
| Washington WSH | | | | Max Scherzer vs Clayton Kershaw | |
| Philadelphia PHI | | | | Matt Moore vs Drew Smyly | |
